产品货号：
Z23781
中文名称：
Plectin/PLEC抗体
英文名称：
Anti-Plectin/PLEC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Plectin/PLEC Antibody |
| 指标别名 | plectin;EBS1;EBSMD;EBSND;EBSO;EBSOG;EBSPA;HD1;LGMD2Q;LGMDR17;PCN1;PLEC1b;PLTN;PLEC |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | PLEC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Plectin (2644-2671aa RFIEQEKAKLEQLFQDEVAKAQQLREEQ),different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids. |
| 实际分子量 | 532KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Plectin,known as PLEC,is a prominent member of an important family of structurally and in part functionally related proteins,termed plakins or cytolinkers,that are capable of interlinking different elements of the cytoskeleton.Plakins,with their multi-domain structure and enormous size,not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape,but also serve as scaffolding platforms for the assembly,positioning,and regulation of signaling complexes.Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans.The plectin gene locus in mouse on chromosome 15 has been analyzed in detail,revealing a genomic exon-intron organization with well over 40 exons spanning over 62kb and an unusual 5' transcript complexity of plectin isoforms.Eleven exons (1-1j) have been identified that alternatively splice directly into a common exon 2 which is the first exon to encode plectin's highly conserved actin binding domain (ABD). |
| Uniprot ID | Q15149 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | plectin |
| 蛋白名全称 | Plectin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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